NAFLD Fibrosis Score Calculator

NAFLD Fibrosis Score (NFS) for non-invasive prediction of advanced liver fibrosis.

For educational and clinical reference. Not a substitute for medical judgment. See the medical disclaimer.
NAFLD Fibrosis Score
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Interpretation
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References

  1. Angulo P, Hui JM, Marchesini G, et al. The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology. 2007;45(4):846-854.

How to use

  1. Enter age, BMI, AST, ALT, platelets, albumin, and tick the diabetes/IFG box if present.
  2. The NAFLD Fibrosis Score and probability band update instantly.
  3. Combine with FIB-4 — concordant low values reliably exclude advanced fibrosis.

Frequently asked questions

What is the NAFLD Fibrosis Score?

A non-invasive score (NFS) estimating the probability of advanced fibrosis (F3–F4) in non-alcoholic fatty liver disease from 6 routine variables.

How is the NFS interpreted?

< −1.455 makes advanced fibrosis unlikely; > 0.675 makes it likely; values between are indeterminate.

NFS vs FIB-4?

Both are validated first-line non-invasive tests in NAFLD/MASLD; they are often used together, with concordant low values reliably excluding advanced fibrosis.

What counts as impaired fasting glucose / diabetes here?

Tick the box if the patient has impaired fasting glucose or established diabetes mellitus — it contributes a fixed term to the score.

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