CKD-EPI 2021 Creatinine eGFR

Estimate glomerular filtration rate (eGFR) using the 2021 race-free CKD-EPI creatinine equation. Output classified by KDIGO CKD stage.

For educational and clinical reference. Not a substitute for medical judgment.
eGFR
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KDIGO Stage
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References

  1. Inker LA, Eneanya ND, Coresh J, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med. 2021;385(19):1737-1749.
  2. Delgado C, Baweja M, Crews DC, et al. A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease. Am J Kidney Dis. 2022;79(2):268-288.

What is CKD-EPI 2021 Creatinine eGFR?

The CKD-EPI 2021 creatinine equation estimates glomerular filtration rate (eGFR) from serum creatinine, age, and sex, without a race coefficient. Developed by the Chronic Kidney Disease Epidemiology Collaboration and published by Inker et al. in the New England Journal of Medicine in 2021, it was endorsed by the National Kidney Foundation and the American Society of Nephrology after evidence showed the previous race-based formula overestimated eGFR in Black patients and delayed care. The output (mL/min/1.73 m²) is mapped to KDIGO CKD stages G1 (≥90) through G5 (<15). It is the recommended equation for CKD diagnosis and staging in adults.

How to use

  1. Enter age, serum creatinine, and sex.
  2. eGFR and KDIGO CKD stage update instantly.
  3. Use the copy button to copy results.

Frequently asked questions

What is the 2021 CKD-EPI equation?

A race-free formula for estimating glomerular filtration rate (eGFR), recommended by the NKF-ASN Task Force.

Why was race removed?

The race coefficient in the 2009 equation was found to overestimate eGFR in Black patients. The 2021 equation eliminates that coefficient.

CKD-EPI or Cockcroft-Gault for drug dosing?

Most drug labels still reference Cockcroft-Gault for renal dose adjustment. CKD-EPI is preferred for CKD staging and prognosis.

What are the KDIGO eGFR categories?

G1: ≥ 90 • G2: 60–89 • G3a: 45–59 • G3b: 30–44 • G4: 15–29 • G5: < 15 mL/min/1.73 m².

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