Mayo Score for Ulcerative Colitis Calculator

Full Mayo score for ulcerative colitis disease activity (0–12).

For educational and clinical reference. Not a substitute for medical judgment. See the medical disclaimer.

Stool frequency (relative to normal for this patient)

Rectal bleeding

Endoscopic findings

Physician global assessment

Score

—

Interpretation

—

References

Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. N Engl J Med. 1987;317(26):1625-1629.

How to use

Select stool frequency, rectal bleeding, endoscopic findings, and physician global assessment.
The total Mayo score (0–12) and activity band update instantly.
For follow-up without endoscopy, use only the first, second, and fourth items (partial Mayo).

Frequently asked questions

What is the Mayo score?

A 0–12 composite index of ulcerative colitis activity combining stool frequency, rectal bleeding, endoscopic findings, and physician global assessment.

What is the partial Mayo score?

The partial (non-invasive) Mayo score omits endoscopy (0–9) and is used for clinic follow-up when colonoscopy is not repeated.

What defines remission and response?

Clinical remission is typically a total Mayo ≤ 2 with no subscore > 1; clinical response is a decrease ≥ 3 points and ≥ 30%, with a bleeding subscore of 0–1.

Why include endoscopy?

Endoscopic activity (mucosal healing) is a key treatment target predicting better long-term outcomes, so the full Mayo score is preferred for trial endpoints.

Last updated June 28, 2026