Lille Model Calculator (Alcoholic Hepatitis)

Lille model for day-7 corticosteroid response in severe alcoholic hepatitis.

For educational and clinical reference. Not a substitute for medical judgment. See the medical disclaimer.

Age (years)

Albumin at day 0 (g/L)

Bilirubin at day 0 (mg/dL)

Bilirubin at day 7 (mg/dL)

Prothrombin time (s)

Renal insufficiency (creatinine > 1.3 mg/dL)

Lille score

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Interpretation

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References

Louvet A, Naveau S, Abdelnour M, et al. The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids. Hepatology. 2007;45(6):1348-1354.

Enter age, day-0 albumin, day-0 and day-7 bilirubin, prothrombin time, and renal status.
The Lille score (0–1) and responder/non-responder interpretation update instantly.
Apply on day 7 of corticosteroids — a score ≥ 0.45 indicates non-response.

A model that predicts 6-month survival in severe alcoholic hepatitis by assessing response to corticosteroids after 7 days of treatment.

A score ≥ 0.45 indicates corticosteroid non-response, with ~25% 6-month survival — supports stopping steroids and considering other options.

Age, day-0 albumin, day-0 and day-7 bilirubin, prothrombin time, and presence of renal insufficiency.

On day 7 of corticosteroid therapy for severe alcohol-associated hepatitis (typically those with a Maddrey DF ≥ 32).

Last updated June 28, 2026