Estimated Blood Volume (Nadler)

Estimate total blood volume from weight, height, and sex using the Nadler formula.

For educational and clinical reference. Not a substitute for medical judgment. See the medical disclaimer.
Estimated Blood Volume
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References

  1. Nadler SB, Hidalgo JU, Bloch T. Prediction of blood volume in normal human adults. Surgery. 1962;51(2):224-232.

How to use

  1. Enter weight (kg), height (cm), and sex.
  2. Total blood volume is shown in mL and L.
  3. Useful for transfusion and plasmapheresis planning.

Frequently asked questions

How is blood volume estimated?

The Nadler formula uses height, weight, and sex: Male: (0.3669 × H_m³ + 0.03219 × W + 0.6041) × 1000 mL. Female: (0.3561 × H_m³ + 0.03308 × W + 0.1833) × 1000 mL.

When is this useful clinically?

Estimated blood volume is used in transfusion planning, plasmapheresis dosing, blood salvage calculations, and to assess significance of acute blood loss.

How does this differ from typical "70 mL/kg"?

The 70 mL/kg rule is a simple estimate. Nadler is more accurate because it accounts for height (and therefore body composition), not just weight.

Does this work for children?

Nadler is validated for adults. Pediatric blood volume estimates vary by age: neonate ~85 mL/kg, infant ~80 mL/kg, child ~75 mL/kg.

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