Sodium Correction for Hyperglycemia

Correct serum sodium for hyperglycemia using the Katz formula.

For educational and clinical reference. Not a substitute for medical judgment. See the medical disclaimer.
Corrected Sodium
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References

  1. Katz MA. Hyperglycemia-induced hyponatremia — calculation of expected serum sodium depression. N Engl J Med. 1973;289(16):843-844.
  2. Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med. 1999;106(4):399-403.

How to use

  1. Enter measured sodium and current glucose.
  2. Corrected sodium appears instantly.
  3. Useful in DKA, HHS, and severe hyperglycemia.

Frequently asked questions

Formula?

Katz: Corrected Na = Measured Na + 1.6 × ((Glucose − 100) / 100).

Why correct sodium?

Hyperglycemia draws water from cells into the extracellular space, diluting serum sodium. Correction reveals the true sodium balance.

Katz vs Hillier?

Katz (1.6 factor) is the classical correction. Hillier 2004 proposed a factor of 2.4 based on euglycemic clamp studies. Clinical guidelines still commonly cite Katz; some sources prefer Hillier in severe hyperglycemia.

When useful?

In diabetic ketoacidosis (DKA), HHS, and other hyperglycemic crises with hyponatremia.

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