Opioid Conversion Calculator

Convert between opioid doses (oral & IV). Reduce calculated dose by 25–50% when switching.

For educational and clinical reference. Not a substitute for medical judgment. See the medical disclaimer.
Equivalent dose
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References

  1. CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022. MMWR Recomm Rep. 2022;71(3):1-95.
  2. McPherson ML. Demystifying Opioid Conversion Calculations. ASHP; 2018.

How to use

  1. Select source opioid + dose and target opioid.
  2. Equivalent dose appears instantly.
  3. Reduce by 25–50% for incomplete cross-tolerance.

Frequently asked questions

What is MME?

Morphine Milligram Equivalents — a common unit normalizing opioid dose to oral morphine for comparison and total daily MME calculations.

Conversion ratios used?

30 mg oral morphine = 10 mg IV morphine = 20 mg oral oxycodone = 7.5 mg oral hydromorphone = 1.5 mg IV hydromorphone ≈ 100 mcg IV fentanyl ≈ 200 mg oral codeine ≈ 200 mg oral tramadol.

About methadone?

Methadone conversion is non-linear and dose-dependent (chronic use changes conversion ratios). Always consult specialty references; this tool gives a conservative chronic-use estimate only.

Why reduce dose when switching?

Cross-tolerance between opioids is incomplete. Most guidelines recommend reducing the calculated equivalent by 25–50% when switching opioids.

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